|Aliases:||Abuela, Abuelita (Santana)|
|Family & Friends|
|Family:|| Dr. Lopez (son)|
|Relationships:||Mr. Lopez (husband)|
|First appearance:||I Kissed a Girl|
|Last appearance:||Goodbye (mentioned)|
Alma Lopez is a grandmother of Santana Lopez, whom she looks up to. She comes across as quite ruthless and, it seems, she is where Santana gets her abrasive nature from.
She only makes a minor appearance in I Kissed a Girl, but is mentioned in a few other episodes.
Alma Lopez is portrayed by Ivonne Coll.
Santana mentions that her abuela (grandmother in Spanish) is not a nice lady, and tried to sell her once. Also, Santana mentions that it had taken until kindergarten to realize that her name was not 'Garbage Face'. However, it was possible she was referring to another grandmother because she looks up to Alma.
Alma is introduced as Santana's grandmother, whom she loves dearly. After Santana comes out to her, she gets angry and tells her that "some secrets are best kept as secrets," and kicks her out of the house. She then storms out of the kitchen, leaving a heartbroken Santana crying in the kitchen. This is the first and last time Alma appears on Season Three. It is unknown if she will appear in future episodes.
When asked about the things they want in the future, Santana mentions that she wants her abuela to love her again some day.
Santana mentions her, mentioning how she didn't accept Santana's sexuality. Maribel Lopez mentions her disappointment in her mother-in-law's inability to accept Santana's sexuality, but shrugs it off.
- Santana mentions in Mash Off that her grandmother is not a nice lady and tried to sell her once. It is unknown as to whether she was referring to Alma or her other grandmother, although it may be the latter as Santana looks up to Alma.
- She is from the Dominican Republic, as the Dominican Flag is seen on her fridge in I Kissed a Girl.
- She had a picture of Santana on her fridge in I Kissed a Girl.
Santana, are you pregnant? Because I will beat you up with this chair.
—Alma Lopez to Santana, I Kissed a Girl